九十年代中期,李牛妞在高考前后,家庭发生了很大意外,命运出现转折。因家庭矛盾,李牛妞的三妹离家出走,造成了小弟瘫痪在床,压力过大的父亲在外出时不幸车祸去世,奶奶又病危住院。一系列灾难,使这个有着三个姓的七口之家的生活跌入低谷。这时,李牛妞毅然决定放弃学业,协助母亲撑起张家的天,既照顾瘫痪的小弟,又照顾长期患病的奶奶,一人担负起了整个家的责任。八年如一日,李牛妞的努力使小弟恢复健康并考上大学。宋超为报师恩,对张家无私奉献,与牛妞终成眷属。三妹桀骜不驯,又非常任性,给家庭带来诸多灾难,但牛妞仍然不离不弃,在三妹患白血病时为其捐献了骨髓,并最终感动三妹,使她认识到了亲情的重要性。李牛妞从开小饭馆到负责一个大型企业集团,自立自强,在亲人的帮助下,最终事业有成。
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